Business & Startups
Entrepreneurship, scaling, leadership, management, company building, culture
Podcasts
The Prof G Pod with Scott Galloway
178 episodesThe Joe Rogan Experience
147 episodesThe Diary of a CEO with Steven Bartlett
119 episodesMasters of Scale
108 episodesMy First Million
107 episodesThe Tim Ferriss Show
98 episodesThe Ed Mylett Show
92 episodesThe Knowledge Project
89 episodesThis Week in Startups
83 episodesGood Life Project
78 episodesThe Art of Charm
77 episodesThe Twenty Minute VC
76 episodesThink Fast, Talk Smart
74 episodesInvest Like the Best
73 episodesThe All-In Podcast
72 episodesAcquired
62 episodesHow I Built This
60 episodesPivot
49 episodesAkimbo: A Podcast from Seth Godin
46 episodesFounders
44 episodesJocko Podcast
40 episodesThe Tony Robbins Podcast
40 episodesDesign Matters
38 episodesThe Marie Forleo Podcast
35 episodesTropical MBA
33 episodesInfinite Loops
30 episodesLenny's Podcast
30 episodesStratechery
29 episodesNot Overthinking
19 episodesDeep Dive with Ali Abdaal
16 episodesRecent Episodes
Michele Steele
The NFL remains the world's most valuable sports business, but its continued growth raises uncomfortable questions. Sports journalist Michele Steele joins to break down the economic forces driving record franchise valuations and exploding quarterback salaries, the league's push into international markets with nine games this season, and the 'Helmets Off' strategy aimed at growing the female fan base. The conversation also confronts the CTE question that won't go away: has the sport actually gotten safer, or have fans been sold a reassuring story?
Walter Russell Mead
Walter Russell Mead discusses the historical pattern that has allowed the US, Britain, and the Dutch to repeatedly defeat centralized continental rivals. He outlines his five-point playbook for global dominance and analyzes how Trump turned fame into political power. The conversation also covers the four schools of American foreign policy, the rise of tech Hamiltonians, how drone warfare is reshaping military power, and why deterrence is eroding in the Middle East.
Alice Han, James Kynge, Ruby Wang
Alice Han and James Kynge preview President Trump and President Xi’s September 24 meeting in Washington, set against a flurry of Xi’s diplomatic activity and shifting trade leverage around rare earths, soybean purchases, and the AI arms race. Then, Ruby Wang joins to discuss China’s biotech boom — how faster, cheaper clinical trials and billions in licensing deals have turned the country into a global pharma challenger, and what it means for U.S. competitiveness. A timely look at the broader US-China rivalry beyond the trade deficit.
Dr. Ben Carson
Dr. Ben Carson shares his remarkable journey from poverty in Detroit to becoming a world-renowned neurosurgeon, and why he entered the presidential race despite having no personal desire for the office. He offers a rare inside look at leadership in the Oval Office, his relationship with Donald Trump—including what he told him while still a primary rival—and the lessons he learned about decision-making and conflicting personalities at the highest levels of government. Carson also reflects on why Americans must relearn how to disagree without demonization, and recounts the dramatic faith transformation that turned an angry teenager who almost took a life into a surgeon who spent his career saving them.
Rick Springfield
Rick Springfield, the Grammy Award-winning musician, actor, and author, joins Joe Rogan. In addition to his solo career, Springfield fronts the rock supergroup The Locustz, whose latest album "Buzzkill" is available now.
The hosts open by recapping recent interviews and the state of American science, then move to China's robotics showcase, Tesla's Optimus update, and the Grok Bot. They analyze Nvidia's and Salesforce's earnings as a reversal of AI capex bubble and SaaS collapse narratives. The discussion turns to Stanley Druckenmiller's criticism of Treasury Secretary Scott Bessent over bond market interventions, followed by the controversy around Druckenmiller using AI to write a Wall Street Journal op-ed. The hosts also cover a CIA director's trip to Moscow and Meta's settlement and new teen rules, before closing with a science segment on Moderna's mRNA cancer vaccine.
Tony Robbins
Tony Robbins shares the hidden emotional needs that drive our decisions and explains why external markers like money, status, and freedom often leave people feeling unfulfilled. He explores how social media may amplify shallow drives and how our strongest impulses can quietly work against the life we truly want. The conversation emphasizes that a deeply meaningful life comes from understanding and redirecting these inner forces toward growth and contribution.
Harry Stebbings breaks down a blockbuster week in AI, starting with NVIDIA's $12B acquisition of Poolside and its investments in Mercor and Perplexity. He discusses OpenAI's confirmed 2027 IPO, Anthropic's bold $30 trillion revenue assumption, and Citadel's exit from its AI trade. The episode also covers the boom in open models, Stripe's reacceleration, and VC warnings that customer service, defense, and robotics are overinflated sectors.
AJ and Johnny explore the hidden cost of being too agreeable in the workplace, which they call the "nice tax." They explain how avoiding small conflicts to maintain harmony often backfires, leading to anxiety, resentment, and reduced professional credibility. The episode provides a practical framework for disagreeing constructively without being defensive or aggressive.
Vanessa Van Edwards
Vanessa Van Edwards joins Matt Abrahams to share research-backed strategies for better networking and communication. She explains how nonverbal cues like visible palms, eye contact, and positioning can signal warmth before you speak. Van Edwards offers a practical "conversational feed" system to replace dull small talk with surprising personal stories, and she breaks down charisma as the interplay of projecting both warmth and competence.
Austan Goolsbee
The U.S. economy remains strong, but core inflation is still above the Fed’s target, and the job market is sending mixed signals. Austan Goolsbee, President of the Chicago Fed, explains why the combination of tariffs, war in the Middle East, and six years of above-target inflation has created the most dangerous inflation environment he’s seen. He discusses what Kevin Warsh’s new leadership means for how the central bank will operate. Goolsbee also offers a “grim optimist” view on AI, and shares which metrics business leaders should watch to stay ahead of the Fed’s next move.
Wade Foster
Wade Foster, CEO of Zapier, joins Sam Parr and Shaan Puri to share how he uses AI to automate executive-level tasks. He walks through specific prompts and workflows for building a robot executive staff, having AI argue with him to sharpen thinking, and using AI for hiring. The conversation also touches on personal topics like being a billionaire before 40 and the value of not having a chip on your shoulder.
Becki DeGraw
Wilson Sonsini partner Becki DeGraw joins Jason Calacanis for a Legal Basics deep dive on startup board mechanics. They cover who really controls the board, when investors start earning seats, the difference between a board member and a board observer, and whether a founder can fire a board member. The conversation walks through the board lifecycle from seed stage to Series B, including compensation, confidentiality for observers, high-pressure signing tactics, and director removal.
Rahm Emanuel
Rahm Emanuel joins Jason Calacanis and David Friedberg to discuss American foreign policy, China, Europe's decline, immigration, fiscal health, and education. The conversation moves from his time in the Clinton and Obama administrations to present-day strategic questions about Taiwan and the global economy. Domestic policy debates cover immigration models, college subsidies, and the government's role in markets. The episode closes with a discussion of the DSA and the coalition inside the Democratic Party.
Joe DeRosa
Joe DeRosa joins Joe Rogan on The Joe Rogan Experience. DeRosa is a comedian, actor, musician, restaurateur, and host of the 'Vile and Horrendous' podcast. His latest special, 'I Never Promised You a Rose Garden,' is now streaming on Netflix.
Sam Parr and Shaan Puri explore businesses hiding in plain sight, starting with the economics of lab testing on monkeys and the salad oil crisis. They discuss how noticing overlooked demand, following genuine enthusiasm, reconnecting with childhood interests, and being shameless about self-promotion can surface opportunities. The episode also touches on Sam's upcoming seven-day trip to San Francisco. Show notes reference Paul Graham's essay 'How To Do Great Work' and companies like Charles River and Qoves.
Kevin Gibbon, Matthias Hofmann
This 'Next Unicorns' episode profiles two early-stage startups using robotics to lower the cost of physical-world services. First, Kevin Gibbon of Cytronic describes a robotics-first fulfillment network that packs and ships orders from small, city-adjacent micro-warehouses for cents instead of dollars, with a warehouse he says costs about $1.2 million to stand up versus $50–100 million for Amazon-scale centers. Then, Matthias Hofmann of Eyebot lays out a kiosk-based approach to vision care, where a 90-second automated test produces a doctor-reviewed eyeglass prescription at low cost. Eyebot is testing the model through pilot programs with Walmart and Sam's Club.
Anastasios Angelopoulos
Anastasios Angelopoulos, CEO of AI model evaluation platform Arena, discusses the state of the AI industry. Topics include Chinese models surpassing US benchmarks, the commoditization of models, and why America's open-source community lags behind China. Angelopoulos shares his views on enterprise fears of frontier labs, stubborn inference costs, and the rise of AI-enabled cyberattacks. He also explores the survival odds for neo labs, data as a trillion-dollar market, and whether model providers will swallow the application layer.
Akemi Tsunagawa
Akemi Tsunagawa, founder of Bespoke, shares how her travel concierge chatbot started as humans manually answering queries behind the scenes—a 'fake it till you make it' approach that landed Narita Airport as a client. The conversation explores Japan's tourism boom, the accelerating population decline, and how the labor shortage is driving both AI adoption and a reexamination of immigration policy. Akemi describes her thesis: first solve the labor gap with people, then build the technology to automate, exemplified by Bespoke's expansion into shipyard robots. They also discuss the 'akiya' abandoned home renovation trend and the cultural resistance to foreign labor in Japan.
Kai Ryssdal
Marketplace host Kai Ryssdal joins Matt Abrahams to discuss how to translate complex ideas into clear, engaging messages without losing nuance. They explore how thorough preparation creates the freedom to be present and authentic during interviews and high-stakes conversations. Ryssdal shares practical techniques for asking better questions, earning audience trust, and maintaining confidence under pressure.
Scott Galloway tackles three listener questions in this solo episode. He explains why market timing is a losing game and why long-term investing is the safer bet. He also offers advice on enduring the pressures of a high-stakes corporate job without burning out. Finally, he gives guidance on balancing caregiving for an aging loved one while maintaining your own career and sanity.
Pete Buttigieg
Former US Secretary of Transportation Pete Buttigieg argues that American democracy is facing an existential crisis and that the everyday problems citizens experience are not accidents but the result of deliberate choices. He shares unreported details about the US strike on Iran and the subsequent failed ceasefire, exposes the unfairness of the tax system, warns that AI will disrupt not just jobs but people's identities, and alleges that the administration hid critical information about fallen American troops. The conversation covers the path to saving democracy and the hard reforms almost no one wants to undertake.
Tim Grover
AJ and Johnny sit down with elite performance coach Tim Grover to unpack the mindset behind sustained success. Drawing on his work with Michael Jordan and Kobe Bryant, Grover explains why failure should change you, why focus matters more than time management, and why the smallest details often separate good from unstoppable. The conversation explores the discipline, self-awareness, and sacrifice required to keep winning.
AJ and Johnny
Most people think promotions go to the person doing the best work, but in reality, they often go to the person who looks like they’re already leading the room. AJ and Johnny break down why competence alone leaves high performers overlooked, while confidence, visibility, and strategic positioning capture leadership’s attention. They explain the difference between self-promotion and executive presence, why working harder can keep you stuck, and how promotion decisions are influenced by meeting-room signals. The hosts introduce a practical three-step technique called ‘summarize and steer’ for organizing messy conversations, clarifying decisions, and proposing next steps. It’s a concise guide to building influence and executive presence without waiting for a title.
Jack Raines
Scott Galloway speaks with Jack Raines, author of 'Young Money: A Field Guide to Wealth and Purpose in Your 20s.' They discuss why young people may be over-optimizing for retirement at the expense of actually living, and explore how to balance wealth building with meaningful experiences. The episode also features Galloway's Algebra of Happiness segment, where he advises listeners to start writing.
Chris Guillebeau
Chris Guillebeau discusses his new book, Time Anxiety, exploring the pervasive feeling of always running behind and never being able to relax. He shares actionable approaches that go beyond standard productivity advice—such as a fifteen-minute fix for chronic lateness, an exercise to clarify what you truly want, and a method for working with your natural energy rhythms. The conversation also touches on the shame caregivers often feel about taking time for themselves and a transformative insight from Gretchen Rubin.
Diana Pasulka
Professor of religious studies Diana Pasulka joins Joe Rogan to discuss her latest book, "The Others: UFOs, AI, and the Secret Forces Guiding Human Destiny." The conversation explores how UFO belief systems resemble religious phenomena, the transformative potential of artificial intelligence as a hidden influence on humanity, and the role of government secrecy in shaping modern mythology.
Chris Camillo
Sam Parr and Shaan Puri talk to investor Chris Camillo about his social arbitrage investing strategy and the specific trades he’s betting on in 2026. The conversation covers how he spots early cultural signals in products like Needohs, the power of nerd culture, using information asymmetry, Amazon analysis, and opportunities in podcasting.
Deedy Das, David Weisburd, Lo Toney, Jason Calcanis
The FCC's decision to ban Chinese humanoid robots over security concerns sparked a debate among VCs Deedy Das, David Weisburd, Lo Toney, and Jason Calcanis about where legitimate security stops and regulatory capture begins. The roundtable also covered Stripe's potential acquisition of OpenRouter and the changing landscape of AI tokenomics, the significance of Cursor Start's launch in India for the startup ecosystem, and DoorDash's drone-delivery expansion. They discussed how these moves reflect shifts in competition, infrastructure, and global markets.
Tim Ferriss answers listener questions on a wide range of topics. He discusses how to shift from hyper-optimization to groundedness, the many paths for reinvention in your late 40s, and five meta-skills he believes will outlast the hype around AI. He also explores male friendship as a shoulder-to-shoulder activity, mentions SAINT and TMS as rapid mental health interventions, and shares why kettlebells and thrice-weekly lifting form the core of his injury-resistant fitness routine.
Forrest Galante
Forrest Galante, wildlife adventurer and conservationist, joins Joe Rogan to discuss his upcoming Discovery Channel special "Alien Sharks: Untamed America," airing as part of Shark Week. The conversation also touches on his broader work in wildlife exploration and conservation.
Dr. Péter Fankhauser, Bernt Børnich, Amanda McMaster, Jonathan Hurst
The All-In Podcast hosts a panel of four robotics CEOs exploring the rapid commercialization of humanoid and quadruped robots. ANYbotics' Dr. Péter Fankhauser explains why his company bet on dog-like quadrupeds over humanoids for industrial use and slams the idea of armed robot dogs. Neo's Bernt Børnich announces plans to ship the Neo humanoid in 2026 as an open developer platform and predicts robots will build other robots within three years. Boston Dynamics' Amanda McMaster reveals Spot as the most deployed robot on earth while Atlas pushes the frontier, and she voices concerns about Chinese robotics security risks. Agility Robotics' Jonathan Hurst argues that advances in AI, sensors, and batteries finally make humanoid robots commercially viable after a century of false starts, and discusses the timeline for robots outnumbering humans on factory floors.
Host-only
This episode examines the life and business philosophy of John D. Rockefeller, exploring the principles that built Standard Oil and the greatest private fortune in history. It traces his early influences, the strategic moves that consolidated the oil industry, the public backlash, the antitrust breakup, and his transformative philanthropy. The narrative surfaces lessons about family, competition, leverage, and giving that remain timely.
Brendon Burchard, Jamie Kern Lima, Ryan Serhant, Tom Papa
Ed Mylett brings together conversations with Brendon Burchard, Jamie Kern Lima, Ryan Serhant, and Tom Papa to explore how self-confidence is built, not discovered. The episode covers building self-trust through small daily wins, refusing to let rejection define your future, embodying confidence as a chosen energy before others believe, and embracing your own path without comparison. Each guest shares personal frameworks and stories that reinforce the idea that confidence grows when you believe in yourself before the world gives permission.
Scott Galloway and George Hahn cover three major stories: the threat that cheaper Chinese AI models pose to US dominance, why Oracle’s rising debt is raising concerns about the sustainability of the AI boom, and Derek Thompson’s concept of the “antisocial century,” which examines how modern risk aversion is fueling isolation and weakening the role of friendship.
Kazuhiro Nakashoji
Jason sits down with Yaqumo CEO Kazuhiro Nakashoji in Tokyo to discuss why quantum computing has been perpetually '10 years away.' They dive into the fundamentals of qubits, the extreme fragility of quantum states that makes error correction so difficult, and the strategic decision to spin out university IP into a startup. Nakashoji shares his vision to build the 'Toyota of Quantum' — a reliable, scalable approach — and warns about the coming reckoning for current cryptography, including Bitcoin.
Derek Thompson
Scott Galloway and Derek Thompson discuss the rise of the 'antisocial century' — what growing isolation is doing to happiness, relationships, and politics. They explore optimization culture, young men's digital retreat, AI's economic bubble, moderate drinking myths, the rise of democratic socialism, and practical dating rules for an increasingly isolated world.
Harry Stebbings (host analysis)
Harry Stebbings examines whether Chinese AI models (Kimi, Qwen) pose a genuine threat to OpenAI and Anthropic, debates the merits of a US ban on Chinese open-source AI, analyzes OpenRouter's positioning as an AI routing layer, and unpacks the strategic implications of Stripe's potential acquisition of PayPal. The episode covers infrastructure-heavy AI trends, late-stage venture capital's dominance, and supply chain bottlenecks in semiconductor manufacturing.
John Maxwell
Ed Mylett and John Maxwell answer top listener questions after covering the first seven laws of leadership. Over 15,000 questions were submitted, touching on family, business, leading through uncertainty, and what's ahead for Season 2. The conversation includes personal, off-camera moments between Ed and John, with raw emotion and reflections on the series.
Timothy Alberino
Timothy Alberino, author and explorer, discusses his new annotated edition of the Book of Enoch, one of the most mysterious and influential ancient texts. The conversation explores the historical context of Enoch, its claims about pre-flood civilization, angelic beings, and cosmological descriptions that challenge conventional understanding of ancient knowledge. Alberino explains why this text was excluded from the Biblical canon and what its content reveals about how ancient peoples understood the cosmos and humanity's relationship to higher powers.
Chris Duffy
Chris Duffy, a comedian, writer, and former teacher, explores how humor strengthens communication and builds connection. He and host Matt Abrahams discuss how laughter, curiosity, and emotion transform ordinary conversations into memorable experiences, and why authenticity matters more than perfecting a routine.
Avishai Abrahami
Avishai Abrahami, co-founder and CEO of Wix, discusses the SaaS market's misunderstanding of AI's impact on platform businesses, the economics of AI-powered "vibe coding," the strategic challenges of Wix's Base44 acquisition and massive buyback program, and why most AI customer support startups fail. He argues that Wall Street fundamentally misvalues Wix's core business and makes a contrarian prediction about AI hype cycles.
Jahmy Hindman
John Deere CTO Jahmy Hindman explores how the 200-year-old agricultural company is embedding sensors, data, and machine learning into tractors and farm software to transform food production. The episode covers AI-driven efficiency gains, sustainability applications, and Hindman's vision for fully autonomous farms—a shift that could reshape global agriculture.
Dario Amodei
Harry Stebbings interviews Anthropic CEO Dario Amodei on the state of AI business models, open-source competition, geopolitics, and market consolidation. The episode covers Coinbase's 50% AI spend cut as a signal of market maturation, Anthropic's stance against open-source commoditization, regulatory concerns around Chinese AI, Microsoft's strategic challenges, and the emerging mega-trend of SaaS roll-ups exemplified by Bending Spoons' IPO. Core themes: the AI market is shifting from hype to unit economics, proprietary models face existential threats from open-source, and consolidation will dominate 2026.
Aileen Lee, Mike Maples, Ben Lerer
A VC roundtable featuring Cowboy's Aileen Lee, Floodgate's Mike Maples, and Lerer Hippeau's Ben Lerer examines the current startup funding landscape and the venture hype cycle. The conversation covers rising valuation expectations, the shift away from pre-AI startups, concerns about founders solving today's problems that may not scale into tomorrow's companies, and whether regulatory moves have affected AI company funding.
David Senra discusses lessons from the biography of Soichiro Honda, the founder of Honda Motor Company, based on the book Honda: The Man and His Machines by Sol Sanders.
Leila Hormozi, Nick Santonastasso
Ed Mylett brings together two powerful conversations about identity and self-respect. Leila Hormozi introduces a life-changing filter question that reframes decisions around self-respect. Nick Santonastasso shares his inspiring story of becoming a varsity wrestler despite being born without legs and with one arm, proving that confidence is built through courage and action. Ed challenges listeners to rewrite their internal dialogue because the quality of your life reflects the conversation you have with yourself. Self-respect is built through daily disciplined choices that align with who you want to become.
Reid Hoffman
Reid Hoffman joins Rana on Masters of Scale's Pioneers of AI series to discuss the implications of Anthropic and OpenAI's announced plans to go public. They analyze what drives the valuations of these companies, the strategic timing of their IPOs, and how the public offerings could reshape the AI startup ecosystem. The conversation also covers sovereign wealth fund proposals for AI investment and the question of what makes an AI company defensible today. Hoffman argues that the AI race is not a zero-sum fight.
George Hahn
George Hahn connects the dots across the week's biggest stories: the Iran ceasefire, a decade after Brexit, a SpaceX reality check, and the World Cup's impact on media economics. The episode provides analysis on these current events.
Sam Parr and Shaan Puri walk through everything you need to know about the SpaceX IPO. They start with the basics of what SpaceX actually does, then break down the launch business, Starlink, Starship, and data centers in space. The episode covers valuation debates, Elon Musk's compensation package, and the people who stand to make fortunes. Along the way, they tell the story of how Sam Bankman-Fried missed a $114 billion investment opportunity, and reflect on why optimists tend to win in the long run.
Graham Hancock
Graham Hancock returns to discuss his evidence for a lost advanced civilization, including ancient maps that show Antarctica centuries before its official discovery, the Great Pyramid's encoded knowledge that shouldn't have existed for millennia, and the Amazon as a man-made landscape. He details the comet impact theory that may have triggered a global cataclysm 12,800 years ago, resetting humanity. With heart surgery looming, Hancock shares the urgency behind his life's work and what he's learned from decades of exploration and plant medicine.
David Senra discusses the biography 'Jony Ive: The Genius Behind Apple's Greatest Products' by Leander Kahney, exploring the life and design philosophy of Apple's former chief designer.
Max Levchin
Max Levchin, co-founder of PayPal and founder of Affirm, shares his journey from Soviet Ukraine to building multi-billion dollar companies. He discusses the science fiction that shaped his vision, the harsh realities of socialism that drove his faith in capitalism, and the decision-making principles he lives by. He also dives into the future of commerce with AI agents, why he's betting on transparent lending, and personal stories of cycling, marriage, and the books that changed his life.
Andrew Feldman (Cerebras), Will Marshall (Planet Labs)
Andrew Feldman (Cerebras) and Will Marshall (Planet Labs) discuss their paths to going public, exploring how IPOs impact employees, customers, and business operations. The conversation covers AI's effect on silicon markets, datacenters in space timelines, and how founder-CEOs think about liquidity as they prepare for public markets.
Yoland Yan
Jason Calacanis reacts to Anthropic's call for a global AI slowdown and Bernie Sanders' proposal to seize 50% of major AI companies' stock, exploring what these mean for wealth redistribution and the 2028 election. Yoland Yan demonstrates ComfyUI, the free open-source node-based platform that's become essential for designers and VFX artists, showing how it powers everything from Vegas Sphere experiences to viral ads.
George Hahn
George Hahn hosts the inaugural episode of The Week, a new weekly breakdown of major stories in business, technology, politics, and culture. The episode explores the collision between technological promise and real-world costs, examining skepticism around AI's ROI, Netflix's optimism about Hollywood's AI future, GLP-1 drugs' potential to outpace AI in transformative impact, and Scott Galloway's reversal on military action in Iran after four months of war.
Dan Loeb
Dan Loeb, founder of Third Point hedge fund, discusses his evolution from message board trader to multibillion-dollar investor. He covers Third Point's shift from event-driven strategies to quality and AI investing, the resurgence of short selling as a disciplined craft, a specific homebuilder trade thesis, and his views on criminal justice reform and the Ross Ulbricht pardon.
Kara Swisher & Scott Galloway
Kara Swisher and Scott Galloway discuss the institutional collapse at CBS's '60 Minutes,' Trump's controversial intelligence chief appointment and what it signals about the devaluing of expertise, California's primary results as a referendum on competence, Apple's bet on AI glasses, and the weakness of Trump's AI executive order. The episode weaves together media dysfunction, political risk, and technology strategy.
Dan Loeb
Dan Loeb, founder and CEO of Third Point, reflects on 30 years of investing evolution—from credit and event-driven strategies to quality, thematic technology, and a major credit business. He discusses activist investing at companies like Sotheby's, Sony, and Yahoo, his approach to AI stack investing, the importance of governance, lessons from FTX's collapse, and the power of clear written communication with boards.
Alexandra Sifferlin
Alexandra Sifferlin, a science and health journalist and author of The Elusive Body, explores the diagnostic crisis in modern medicine. Nearly everyone experiences at least one diagnostic error in their lifetime—a missed, delayed, or wrong diagnosis that shapes treatment and suffering. Sifferlin spent years inside hospital systems interviewing leading diagnosticians and tracing families who waited decades for answers, uncovering the structural gaps that let real suffering fall through the cracks. This conversation examines how physicians actually build diagnoses, what gets lost in seven-minute appointments, and what to do when multiple practitioners can't identify your condition.
Scott Galloway
Scott Galloway examines whether long-term investors should diversify away from US equities given recent market dynamics, argues that acquiring a boomer-owned small business offers better risk-adjusted returns and autonomy than staying in corporate America, and reflects on his predictions from The Four a decade later to assess which tech giants have held their dominance.
Josh Thompson, Big John McCarthy
Joe Rogan hosts retired MMA champion Josh Thompson and legendary referee Big John McCarthy to discuss the evolution of mixed martial arts, refereeing standards, and the sport's current landscape. Thompson and McCarthy, co-hosts of the "Weighing In" podcast, bring decades of combat sports experience to analyze rule changes, fighter safety, and the technical aspects of what makes great refereeing in MMA.
Bobby Healy, Ian Laffey
Bobby Healy, founder of Manna, explains how his Dublin-based drone delivery company completed 300,000 deliveries while competitors are still in early stages, and why low-cost airline economics will determine winners in autonomous delivery. The episode also features Ian Laffey from Theseus, discussing how camera-based drone guidance systems using Google Maps could reshape GPS-jammed battlefields and level the playing field for smaller nations. Both founders represent different applications of drone autonomy—logistics and defense—that are moving from theoretical to operational.
Kara Swisher, Scott Galloway
Kara and Scott discuss Elon Musk's loss in the OpenAI trial, OpenAI's brewing legal battle with Apple over ChatGPT integration into Siri and iOS, and Trump's stock trading activity. The episode also covers new SpaceX IPO governance details and Spencer Pratt's unexpected entry into the L.A. mayoral race.
Erin Weed
Erin Weed, speaker coach and creator of the Dig—a purpose-excavation method—explores how a single word can reveal your life's operating system. In this episode, Jonathan undergoes the full Dig process in real time, uncovering the hidden patterns in his life story and discovering the word that has been running his life all along. The conversation reveals why most people are wrong about their defining word, how violations and anger point to your core purpose, and how knowing your word transforms decision-making.
Jason Calacanis, Alex (co-host)
Jason Calacanis and Alex discuss the growing backlash against AI among Gen Z and the broader public, triggered by high-profile figures like Eric Schmidt being booed at commencement ceremonies. The episode explores why students entering an AI-reshaped job market are increasingly skeptical of the technology, examines concentration of AI revenue (90% to Anthropic and OpenAI), and covers emerging concerns about surveillance infrastructure like Flock Safety's camera networks.
Marcus King
Marcus King, lead singer, guitarist, and founder of The Marcus King Band, talks with Joe Rogan. The conversation touches on his recent album “Darling Blue,” his musical career, and life as a touring artist.
Gad Saad
Dr. Gad Saad joins Joe Rogan to discuss his new book 'Suicidal Empathy: Dying to Be Kind.' The conversation explores the dangers of excessive, unmoored empathy and the perverse outcomes that arise when kindness detaches from reason. (Full details are limited due to the lack of detailed show notes; listeners should check the episode for more.)
Scott Galloway reads his latest "No Mercy / No Malice" essay, "Apocalypse No," sharing his analysis of current events or trends.
Kara Swisher, Scott Galloway
Kara and Scott discuss Ted Turner's legacy and its impact on media, unpack earnings from Warner Bros. Discovery, Paramount, and Disney, explore Anthropic's partnership with SpaceX, analyze the Elon Musk vs. OpenAI trial, and test ChatGPT's ability to pick winning stocks in real markets.
Julia Mossbridge
Julia Mossbridge, a cognitive neuroscientist and founder of Applied Love Labs, discusses her research on consciousness, precognition, and the intersection of neuroscience and human connection. The conversation explores her latest book 'Have a Nice Disclosure!' and her work applying neuroscience to understand love, relationships, and anomalous human capacities.
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg
The All-In besties debate Elon's SpaceX-Anthropic compute partnership, whether Anthropic is becoming an AI monopoly, White House "FDA for AI" regulation talk, and opportunities in AI market trading. Discussion spans infrastructure economics, antitrust concerns, policy risks to AI innovation, and how AI is shifting from a negative perception problem to a positive impact play in healthcare and education.
Amjad Masad
Sam Parr and Shaan Puri interview Replit founder Amjad Masad about his company's meteoric rise from 2.5 million to 250 million users in a year following the AI Agent launch. They discuss the near-death moment that forced multiple pivots, the experience of living through a technological singularity, and Amjad's personal strategies for staying calm under pressure.
Todd Graves
Todd Graves, founder and CEO of Raising Cane's Chicken Fingers, joins host Jeff Berman to discuss how he built the nearly 1,000-unit restaurant chain. He emphasizes the power of a simple menu and friendly staff culture as key drivers of success. Graves also shares his cautionary view on private equity for restaurants. The conversation covers the recipe for scaling a focused brand.
Gary Stevenson
Gary Stevenson, a former trader turned economist and inequality activist, argues that modern Western economies increasingly reward ownership over work, accelerating wealth concentration among billionaires while the middle class shrinks and younger generations face the prospect of becoming poorer than their parents. Scott and Gary explore whether wealth taxes, estate taxes, and stricter tax enforcement could reverse these trends.
David Senra rereads Shoe Dog, Phil Knight's memoir about building Nike, and reflects on the lessons that have stuck with him across multiple readings.
Tim Burchett
Rep. Tim Burchett (R-TN) discusses his work in Congress, including his role as chairman of the DOGE Subcommittee and membership in the UAP Caucus. The conversation covers government accountability, oversight responsibilities, and legislative priorities across defense, foreign affairs, and infrastructure.
Anne Lamott, Claire Hughes Johnson, David Yarrow, Diana Chapman
In this compilation episode, Tim Ferriss poses a single question to four past guests—Anne Lamott, Claire Hughes Johnson, David Yarrow, and Diana Chapman—asking each to share 1-3 decisions that could dramatically simplify life in 2026. The episode brings together perspectives on clarity, responsibility, creativity, and intentional living.
Alice Han, James Kynge
Alice Han and James Kynge discuss three major developments in China: the accelerating space race with the US, a $2 trillion generational wealth transfer without inheritance tax, and the spread of AI automation into dim sum kitchens, with regulators potentially setting a global governance standard.
Ankur Nagpal, Jon Durbin, Yash Goenka
Ankur Nagpal from AngelList discusses USVC, a new venture capital fund that allows unaccredited investors to invest as little as $500 with quarterly redemptions. Later, Jon Durbin presents Chutes, a Bittensor subnet aggregating GPUs for trustless AI compute, and Yash Goenka introduces Humwork, which adds human intervention to unstuck AI agents. The episode also covers a news lightning round.
Chris Todd
Private investigator Chris Todd details overlooked evidence from the O.J. Simpson case, including additional blood spatter, multiple footprints, and investigative inconsistencies. He argues that the crime scene suggests multiple people may have been involved, challenging the lone‑killer narrative presented at trial. Ed Mylett presses him on the timeline, logic, and gaps in the official investigation, offering a thought‑provoking re‑examination of the case.
Kara Swisher and Scott Galloway discuss GameStop's $55 billion bid for eBay and the CEO's disastrous CNBC interview, the rise of AI-funded super PACs copying crypto industry tactics to influence the midterms, the Senate's ban on member trading in political prediction markets, new Pentagon AI contracts, and what Apple's latest earnings say about its future.
Rohan Oza
Sam Parr and Shaan Puri sit down with Rohan Oza, the 'Brandfather' behind Vitaminwater, Bai, and Popchips, to dissect his formula for building consumer brands into multi-billion-dollar exits. Oza lays out his two core rules: influence the influencer instead of mass advertising, and make your brand a pop culture icon. He also reframes retail as 'the original algorithm,' shares how he spots winning products by evaluating tastebuds and TAM, and tells the story of Poppi’s explosive growth after Shark Tank. The conversation is a masterclass in turning simple consumer products into household names.
Chamath Palihapitiya
Chamath Palihapitiya, venture capitalist, founder of Social Capital, and co-host of the 'All-In' podcast, joins Joe Rogan. The conversation covers a range of topics related to technology, investing, and current events.
Mellody Hobson
Mellody Hobson, co-CEO of Ariel Investments and former chair of Starbucks and DreamWorks, shares her contrarian investment philosophy. She argues that market volatility should be exploited, not merely survived, and reveals a personal financial rule: never let money drive your decisions. She identifies women's sports as a generational investment opportunity and explains why 'math has no opinion' can change how you see risk.
Julia Minson
Julia Minson, behavioral scientist and Harvard Kennedy School professor, joins to discuss the science of disagreeing well. Her book 'How to Disagree Better' provides a research-backed framework for navigating conflict without damaging relationships. The conversation reveals why leading with facts often backfires and the importance of practicing on low-stakes disagreements. Minson also explains why empathy is unreliable in heated moments and what to focus on instead. This episode offers practical tools for anyone who wants to stay connected across deep differences.
Tobi Lütke
Tobi Lütke, CEO of Shopify, discusses his reluctance to become CEO, the impact of AI on entrepreneurship and labor markets, and why he believes companies are using AI as a scapegoat for layoffs. He also critiques charitable giving inefficiency, government dysfunction, and Canada's political reaction to Trump, while offering career advice based on compound learning and skill differentiation.
Will Edwards (Firehawk Aerospace), Maruchi Kim (VueBuds)
Jason Calacanis interviews Will Edwards of Firehawk Aerospace, a defense tech startup that applies 3D-printed solid rocket propellant to cut missile production costs in half and increase U.S. output by 5x—addressing a critical U.S. military shortage. The episode also features Maruchi Kim discussing VueBuds, camera-equipped earbuds that match Ray-Ban Meta smart glasses performance and represent an emerging wearable AI platform.
Amjad Masad
Amjad Masad, CEO of Replit, discusses why AI coding models are hitting performance plateaus and why this matters for the future of development tools. He explains Replit's strategy of not building their own model, why product quality beats cost optimization, and makes a provocative case that the SaaS apocalypse—where AI displaces traditional software—is justified and inevitable. Masad also challenges narratives about IDEs being dead, addresses whether PMs survive the next 3-5 years, and reflects on what true product-market fit actually means.
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg
The All-In besties discuss SpaceX's acquisition of Cursor for compute leverage, the emerging SaaS debt crisis with major firms like Medallia facing creditor pressure, Tim Cook's succession to John Ternus at Apple and what it means for the company's future, the SPLC indictment raising questions about NGO oversight, and new research linking a specific microbiome imbalance to the surge in colon cancer among young adults.
Dylan Patel
Dylan Patel, founder of SemiAnalysis, discusses the explosive demand for frontier AI models and the supply constraints limiting their scaling. He explains why frontier models command nearly unbounded willingness to pay, how his firm's AI spending has grown from tens of thousands to $7M in a year, and the critical bottlenecks in memory, logic, and fab equipment that will determine how fast AI infrastructure can scale. The conversation also covers perception challenges facing leading AI labs.
Chris Zacharia, Brian McRindle (Bitstarter); Ning Ren (Trajectory RL)
SpaceX and Cursor announced a $10B partnership to develop AI coding models, with an option for a $60B acquisition. The episode explores the deal's implications for the AI coding market, then dives into Bittensor infrastructure through Bitstarter (a 'Kickstarter for Bittensor subnets') and Trajectory RL's use of decentralized competitions to design AI agent skills. Discussion spans the economics of AI compute consolidation, decentralized AI infrastructure, and the emerging role of 'skills' as critical building blocks in the agentic era.
Ben Gilbert & David Rosenthal
The definitive Acquired episode on Amazon: Jeff Bezos from D.E. Shaw quant to building the everything store. The Prime flywheel, AWS as an accidental trillion-dollar business, the Day 1 philosophy, and how Bezos created the most customer-obsessed company in history.
Chamath Palihapitiya
The hosts debate the Department of Government Efficiency (DOGE), Elon Musk's initiative to cut government spending. Can Silicon Valley's move-fast mentality work in bureaucracy?
Chamath Palihapitiya
Emergency episode after the 2024 presidential election. The hosts analyze Trump's victory, the role of tech billionaires in the campaign, and what the result means for AI policy, crypto regulation, and tech antitrust.
Chamath Palihapitiya
Heated debate on AI regulation. Sacks argues for minimal regulation to preserve innovation. Friedberg argues for targeted safety requirements. Chamath and Calacanis stake out middle ground.
Ben Gilbert & David Rosenthal
Brian Chesky, Joe Gebbia, and Nate Blecharczyk built Airbnb from air mattresses on a living room floor to an $80B+ travel platform. The complete story of surviving Obama O's, Y Combinator, the pandemic collapse, and the design-driven reinvention.
Chamath Palihapitiya
The hosts debate Silicon Valley's political shift rightward. Why tech founders who were reliably Democratic are now supporting Republican candidates, and what this means for technology policy.
Chamath Palihapitiya
The four besties make their annual predictions for 2024: AI progress, market performance, election outcomes, and geopolitics. Each host puts their reputation on the line with specific, falsifiable predictions.
Ben Gilbert & David Rosenthal
The full Apple story: from the garage to $3T. How Steve Jobs and Steve Wozniak built the most valuable company in history through an obsessive focus on product quality, vertical integration, and the intersection of technology and liberal arts.