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Canon
Glutathione: The Body’s Master Antioxidant
research · Biochemical research on antioxidant systems (2026)
Confidence: High
Glutathione is the body's primary intracellular antioxidant, essential for detoxification, mitochondrial function, and immune defense.
Core Concepts
The Problem
Oxidative stress damages cells, accelerating aging and disease.
The Claim
Glutathione is the body's primary intracellular antioxidant, essential for detoxification, mitochondrial function, and immune defense.
Key Evidence
- •Endogenously produced and present in all cells
- •Critical for neutralizing free radicals and reactive oxygen species
- •Levels decline with age and chronic stress
Practical Implication
Supporting glutathione levels may help maintain cellular health, energy, and cognitive function.
Nuance & Limits
Most oral supplements are poorly absorbed; delivery methods are key to clinical benefit.
Source Material
Citation Density
High
Gaps
- ⚠ Optimal dosing and long-term safety of supplementation need more research
- ⚠ Variability in individual glutathione synthesis pathways not fully understood
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