Type 2 Diabetes Remission in the GLP-1 Era

Professor Roy Taylor returns three years after his first appearance to discuss the definitive five-year results from the DiRECT trial. The evidence confirms that type 2 diabetes is driven by excess fat in the liver and pancreas, and that substantial weight loss can produce durable remission—but only if the weight stays off. Taylor also breaks down what GLP-1 receptor agonists can really do, where the marketing runs ahead of the science, and why concerns about muscle loss require perspective rather than panic.