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The Human Upgrade · June 28, 2026 · 00:12:25

BONUS: The Anti-Aging Molecule Backed by Nobel Prize Research : 1492

Dave Asprey

Dave Asprey explains the science behind NAD+ as a critical anti-aging molecule supported by Nobel Prize-winning research. He details how age-related declines in NAD+ contribute to fatigue, brain fog, and degeneration, and outlines a comprehensive protocol to restore NAD+ levels, including diet, polyphenols, fasting, REHIT exercise, and NMN/NR supplementation.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

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NAD⁺ Decline Drives Aging
Dave explains that NAD⁺, a critical mitochondrial cofactor, declines with age and its depletion by overactive enzymes leads to cellular dysfunction and aging.
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Highlights

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The NAD⁺ Restoration Protocol
Dave outlines a comprehensive protocol combining diet, polyphenols, fasting, REHIT exercise, and NMN/NR supplementation to restore NAD⁺ levels and slow aging.
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REHIT Exercise for Mitochondrial Health
Dave highlights REHIT (Reduced Exertion High-Intensity Training) as an efficient exercise method to boost NAD⁺ levels.
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