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The Human Upgrade · May 21, 2026 · 53m 6s

The Biblical Anti-Aging Fruit That Scientists Are Obsessed With : 1470

Chris Rinsch, Dave Asprey

Dave Asprey interviews Chris Rinsch, co-founder of Timeline Longevity, about the 18-year development of urolithin A, a postbiotic compound that triggers mitophagy and is backed by extensive clinical research. They discuss how it outperforms rapamycin in clearing damaged mitochondria and its position as one of the most validated longevity supplements. The conversation covers the science of aging at the cellular level and practical applications for healthspan.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Canon

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Urolithin A Triggers Mitophagy
Urolithin A is a postbiotic compound that selectively clears damaged mitochondria through mitophagy.
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Novel

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Urolithin A Outperforms Rapamycin
Chris Rinsch asserts that urolithin A is more effective than rapamycin at clearing damaged mitochondria.
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Highlights

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Postbiotics: A New Category of Longevity Supplement
Urolithin A is derived from ellagitannins in pomegranates and classified as a postbiotic.
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18 Years of Clinical Validation
Timeline’s urolithin A product has been clinically tested across multiple trials over nearly two decades.
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