Don't Wait for Alzheimer's — A Neurologist's 30-Year Plan to Protect Your Brain

Dr. Mark Hyman interviews neurologist David Perlmutter about protecting the brain decades before symptoms appear. Perlmutter explains that Alzheimer's pathology begins long before memory slips, and that daily choices can steer brain immune cells toward a protective state. He outlines key numbers to monitor—like fasting insulin, blood sugar, and waist-to-hip ratio—and details how food, exercise, sleep, gut health, and environmental toxins shape long-term brain health. Emerging research shows that cognitive decline can be slowed and even reversed with the right interventions.