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The Peter Attia Drive #333 · January 27, 2025 · 160m
Longevity roundtable: aging, geroprotective molecules, and lifestyle interventions
Three of the world's leading aging researchers debate: what works, what's hype, and what's coming. Rapamycin, senolytics, GLP-1 agonists, caloric restriction. The consensus: exercise remains the most proven geroprotective intervention. Everything else is promising but unproven in humans.
This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.
Canon
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Austad, Kaeberlein, and Miller agree: despite billions spent on longevity drugs, exercise remains the single most effective intervention for extending healthspan. No molecule comes close to its breadth of effect across every organ system.
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