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The Human Upgrade · October 1, 2026 · 47m 3s

Dave’s Anti-Aging Skincare Routine: Exosomes, Methylene Blue & NAD+ : 1547

Dave Asprey talks with Young Goose co-founders Amitay Eshel and Anastasia Khodzhaeva about skin longevity science. They explain why wrinkles are only a surface sign of deeper cellular aging, involving mitochondrial decline, oxidative stress, and senescence. The discussion covers metabolomics-based skin metabolic age testing, methylene blue, NAD+ precursors, vampire exosomes, red light therapy stacking, senomorphics, and emerging proteomics. Practical routines for travel and personalized skincare via AI are also explored.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Preview

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Skin aging is a cellular, not cosmetic, issue01:09
Wrinkles are only one visible sign of deeper cellular aging driven by mitochondrial dysfunction, oxidative stress, and senescence.
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Metabolomics-based skin metabolic age testing01:09
Young Goose offers a metabolomics test that estimates skin metabolic age from a blood sample analyzing 17 metabolites.

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