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The Human Upgrade · August 18, 2026 · 2h 46m

Scream Cream and Weekly Injections (Double Episode) | Gabby Reece : 1521

Dave Asprey and Gabby Reece sit down for a double interview exploring hormone optimization after 50, mitochondrial function, and longevity protocols. Gabby shares how weekly testosterone injections and a compounded vasodilation cream—"scream cream"—resolved a heart arrhythmia that doctors initially misdiagnosed as a cardiac issue. Dave explains his theory that autism can bring cognitive superpowers once physical symptoms are addressed, outlines his personal cancer-prevention protocol involving antifungal agents and infrared light, and details the peptides he uses for mitochondrial renewal including SS-31 and Russian bioregulators. The conversation also covers cyclical ketosis, why Dave avoids GLP-1 drugs despite their longevity potential, and what both have learned about surrender versus control in building a life around high performance.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Preview

Testosterone Therapy for Women's Heart Arrhythmia02:22:44
Gabby's heart arrhythmia was misdiagnosed as a cardiac issue; it resolved when she treated her hormones with weekly testosterone injections and an estradiol patch.
Scream Cream: Compounded Vasodilation Hormone Therapy02:22:44
Gabby uses a compounded topical hormone cream known as "scream cream" that works through vasodilation, commonly prescribed alongside hormone replacement therapy.

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