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The Human Upgrade · August 7, 2026 · 10m 33s

Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515

Dave Asprey

This roundup covers a drug-repurposing screen that searched existing medications for longevity benefits, the protein restriction mechanism through FGF21, a new injectable derived from cadaver tissue for skin rejuvenation, new evidence that arts engagement slows biological aging, and a systematic review of 41 studies testing biohacking interventions against epigenetic clocks.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Canon

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Protein Restriction Promotes Longevity via FGF21
Dietary protein restriction triggers FGF21 release, which promotes metabolic health and longevity.
ClaudeChatGPTGemini
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Arts Engagement Slows Biological Aging
Engaging in cultural activities like music, theater, and visual arts appears to slow biological aging.
ClaudeChatGPTGemini
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Systematic Review of Biohacking Interventions vs. Epigenetic Clocks
A meta-review of 41 studies evaluated how various biohacking interventions, from semaglutide to lifestyle changes, affect epigenetic aging clocks.
ClaudeChatGPTGemini

Highlights

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Drug Repurposing Screen for Longevity
Scientists screened existing drugs for compounds that could extend healthy lifespan.
ClaudeChatGPTGemini
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Cadaver-Derived Skin Injectable
A new cosmetic treatment uses injectable material derived from processed cadaver tissue to rejuvenate skin.
ClaudeChatGPTGemini
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