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The Human Upgrade · May 28, 2026 · 01:23:33

Combine Creatine With THIS To Fight The Root Cause of Aging

Dr. Andrew Salzman

Dr. Andrew Salzman joins Dave Asprey to explain how a leaky gut barrier triggers a cascade of NAD depletion and systemic inflammation that accelerates aging. He outlines the mechanism and makes the case that combining creatine with targeted NAD support is key to counteracting this root cause of aging.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Novel

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Gut Barrier Breakdown Is a Root Cause of Aging
Dr. Salzman describes how damage to the gut barrier triggers a chain reaction of NAD depletion and widespread inflammation, which drives systemic aging.
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Highlights

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Creatine Combined With NAD Support May Reverse Gut-Driven Aging
Pairing creatine with targeted NAD support is presented as an effective strategy to counteract the aging cascade that starts in the gut.
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