Essentials: The Science & Treatment of Obsessive Compulsive Disorder (OCD)

In this Huberman Lab Essentials episode, Andrew Huberman explains the biology and psychology of obsessive-compulsive disorder (OCD). He describes how intrusive obsessions and compulsive actions form a self-reinforcing thought-action loop rooted in a specific brain circuit involving the cortex, striatum, and thalamus. The episode covers diagnostic tools like the Yale-Brown Obsessive Compulsive Scale, and reviews evidence-based treatments including exposure-based cognitive behavioral therapy and SSRIs. Huberman also discusses emerging interventions such as TMS, mindfulness, and nutraceuticals.