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The Genius Life · February 23, 2026 · 52m

Brain Health AMA: Dementia Prevention, Memory, and Cognitive Performance

Max Lugavere answers listener questions on dementia prevention: the role of creatine for brain health, why sleep is non-negotiable for memory consolidation, and the supplements with the strongest evidence for cognitive protection.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Canon

Lugavere synthesizes the evidence: exercise, sleep, Mediterranean-style diet, social connection, and cognitive stimulation reduce Alzheimer's risk by 30-60% when started in midlife.
Lugavere reviews neuroimaging studies showing that long-term meditators have larger hippocampal volume, thicker cortical tissue, and reduced age-related brain atrophy compared to non-meditators.
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