Dr. Steve Horvath, creator of the epigenetic clock, joins Dr. Rhonda Patrick to discuss how biological age is measured and how it can be influenced. He explains why clocks like GrimAge and DunedinPACE are powerful predictors of mortality and aging speed, and which are best suited for testing anti-aging interventions. Horvath highlights the strongest evidence to date: omega-3 fatty acids, a daily multivitamin, and adequate vegetable intake can each slow epigenetic aging, with some studies showing up to five years of reversal in months.
This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.
Novel
•
A Daily Multivitamin May Slow Epigenetic Aging01:17:29
Horvath cites randomized controlled trial evidence showing that a daily multivitamin can slow or even reverse epigenetic age as measured by several clocks over a multi-year period.
Omega-3, Vitamin D, and Exercise: Which Slows Aging Best?01:26:11
When comparing three commonly studied anti-aging interventions, Horvath finds that omega-3 fatty acids have the most consistent evidence for slowing epigenetic aging, followed by exercise.