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FoundMyFitness · May 3, 2025 · 65m

Q&A #70: Supplement Timing, Exercise Timing, Folic Acid vs. Folate, Hydrogen Water

Listener Q&A covering supplement timing relative to meals and exercise, whether exercise timing matters for metabolic health, the critical distinction between folic acid and methylfolate, and the evidence (or lack thereof) for hydrogen-rich water.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Highlights

Folic acid vs. methylfolate — genetic variation makes this distinction life-or-death in pregnancy
Patrick: 30-40% of people carry MTHFR variants that impair conversion of synthetic folic acid to active methylfolate. For these individuals, folic acid supplementation may actually be harmful, accumulating as unmetabolized folic acid associated with cancer risk.
Supplement timing relative to exercise matters — some supplements blunt the training response
Patrick: high-dose antioxidants (vitamin C, vitamin E) taken immediately around exercise can blunt the adaptive stress response that makes exercise beneficial. Take antioxidant supplements away from workout windows.
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