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TED Radio Hour · May 15, 2026 · 49m

How to feel alive in an exhausting world

Martin Picard, James Nestor

Why do some people feel perpetually drained while others seem to have boundless energy? Host Manoush Zomorodi explores what science is revealing about stress, breathing, and cellular energy. Guests include mitochondrial psychobiologist Martin Picard, who discusses how mitochondria influence fatigue, and science journalist James Nestor, who explains the role of breathing in vitality. The episode offers insights into how daily habits and physiology shape our energy levels.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Curious

Martin Picard explains how mitochondria respond to stress, and how their function can be impaired, leading to chronic fatigue.
James Nestor discusses how breathing techniques can influence the nervous system and energy levels, drawing on the science of breath.

Highlights

The Fatigue Puzzle: Why Some Stay Energized
The episode explores the question of why some people feel exhausted while others maintain high energy, pointing to a combination of physiological and lifestyle factors.
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