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Sleep Unplugged · October 19, 2026 · 36m
Peptides and Sleep: Sights So High
Dr. Chris Winter tackles the hype around peptides, explaining that the term alone means nothing about efficacy or safety. He breaks down the confusing regulatory categories—FDA-approved drugs, compounded preparations, supplements, and gray-market vials—and discusses the FDA advisory panel's rejection of DSIP, the peptide once touted as a deep-sleep promoter. The episode compares the strong clinical evidence for tirzepatide in sleep apnea against the weak data for epitalon and growth-hormone peptides, and ends with five practical questions to ask anyone pushing peptide therapies.
This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.
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Regulatory gray area: supplements, drugs, and 'research use only' labels
Peptide products fall into confusing regulatory categories, including FDA-approved drugs, compounded pharmacy preparations, dietary supplements, and vials labeled "for research use only," each with different oversight.3 more ideas & all timestamps
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