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Sleep Unplugged · November 17, 2025 · 39m

#178 - Orexin Agonists Are Here: This Is The New Stuff

Chris Winter (solo)

The orexin receptor agonists are coming. After years of managing narcolepsy with stimulants, sodium oxybate, and wake-promoting agents, we soon will have medications that target the root cause of the disorder: the loss of orexin signaling.

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