← Home
The Peter Attia Drive · March 1, 2026 · 120m

Sleep Apnea: The Silent Epidemic

Dr. Raj Dasgupta

80% of sleep apnea cases are undiagnosed. Dr. Dasgupta on how untreated sleep apnea accelerates cardiovascular disease, neurodegeneration, and metabolic dysfunction — and why CPAP compliance is so low.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Canon

•
Untreated sleep apnea is a major driver of Alzheimer's risk
Dasgupta: sleep apnea fragments deep sleep (when the glymphatic system clears amyloid). Chronic untreated apnea accelerates amyloid accumulation and doubles Alzheimer's risk.
ClaudeChatGPTGemini

Highlights

•
CPAP compliance is <50% because the solution ignores human behavior
Dasgupta: CPAP is highly effective when used but fewer than half of patients use it consistently. The device is uncomfortable, unsexy, and requires nightly commitment — a behavior design failure.
ClaudeChatGPTGemini
Was this useful?