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Life Kit · June 22, 2026 · 13m

Should I take a probiotic? And other gut questions, answered

NPR health correspondent Will Stone breaks down what the science says about probiotics, microbiome testing, and the best ways to improve your gut health. He explains that only a few probiotic strains have strong evidence for specific conditions like diarrhea, and that diet is the most powerful tool for a healthy microbiome. The episode also underscores the connection between gut microbes and overall well-being, including mental health.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Highlights

Only a few probiotic strains have strong evidence
Most probiotic supplements lack robust evidence, but two specific strains—Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG—are backed by randomized controlled trials for preventing diarrhea and respiratory infections.
Will Stone emphasizes that when it comes to improving your gut microbiome, your overall dietary pattern—especially variety—matters far more than any single supplement.
The episode reiterates that the trillions of microbes in our intestines don’t just handle digestion—they’re intimately connected to immune function, mental health, and cognition.
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