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FoundMyFitness · October 2, 2025 · 225m
Evidence-Based Testosterone Optimization and TRT
Derek from MPMD evaluates popular testosterone-boosting supplements — tongkat ali, boron, ashwagandha — clarifying what's evidence-based vs. overhyped. Detailed TRT protocols covering delivery methods, fertility implications, and biomarkers to monitor.
This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.
Canon
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Derek: population-level testosterone has declined roughly 1% per year since the 1980s, even after controlling for obesity and age. Environmental endocrine disruptors — phthalates, BPA, PFAS — are a primary driver.
Highlights
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Most testosterone-boosting supplements don't meaningfully raise total testosterone
Derek: of the popular 'natural testosterone boosters,' most produce statistically insignificant changes in total testosterone. Ashwagandha lowers cortisol (which indirectly helps), tongkat ali has modest evidence, but none compare to optimizing sleep, exercise, and body composition.Was this useful?