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The Doctor's Farmacy · August 12, 2026 · 1h 18m

What We Got Wrong About GLP-1s (And What's Right)

Dr. Hyman reconnects with metabolic health and regenerative medicine expert Dr. Tyna Moore to revisit their conversation about GLP-1 medications from two years ago. They examine how to tell when a GLP-1 dose may be too high, how to protect muscle and bone during weight loss, and which metabolic and nutritional markers to monitor before and during treatment. The conversation also covers why weight sometimes returns after stopping a GLP-1 and what emerging research suggests about the drugs' effects beyond weight loss. The central argument is that how these medications are used — from dosing and monitoring to nutrition and strength training — matters as much as whether they are used at all. A lower number on the scale, they argue, is not the same as better health.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Curious

Moore discusses what can be done to protect muscle and bone while losing weight on a GLP-1.
The episode explains why weight can return after a patient stops taking a GLP-1.

Highlights

Recognizing When a GLP-1 Dose Is Too High
Moore explains how to recognize when a GLP-1 dose may be too high.
Metabolic and Nutritional Markers to Track Before and During Treatment
Moore highlights which metabolic and nutritional markers should be checked before starting a GLP-1 and monitored during treatment.
GLP-1 Effects Beyond Weight Loss
The episode touches on emerging research into what GLP-1s may do beyond weight loss.

Editorial

How the Medications Are Used Matters as Much as Whether They're Used
Host and guest argue that dosing, monitoring, nutrition, and strength training determine whether GLP-1 use actually produces better health.

Misc

The episode is a follow-up to Moore's earlier appearance on The Dr. Hyman Show about two years prior.
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