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Conan O'Brien Needs A Friend · September 10, 2026 · 23m 40s

Comedy Crimes with Andy Daly

Andy Daly

Conan O'Brien and comedian Andy Daly connect with Peter, a caller from Framingham, Massachusetts, who works for the CPCS Innocence Program—an organization that uses DNA evidence to exonerate the wrongly convicted. The trio explores the surprising places investigators find DNA, from discarded items to everyday objects, injecting humor into the serious business of justice. They also reflect on how comedy can serve as a bridge during difficult discussions, drawing on their own experiences as performers.

This summary was generated from show notes and public descriptions, not from a full transcript review. Details may contain inaccuracies.

Highlights

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The CPCS Innocence Program and DNA Exoneration
Peter, a caller from Framingham, Massachusetts, shares his experience working for the CPCS Innocence Program, which uses DNA evidence to exonerate the wrongly convicted.

Editorial

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The Most Unusual Sources of DNA
The group discusses the surprising and sometimes comical places investigators can find usable DNA samples, from licked stamps to discarded coffee cups.
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Bringing Comedy into Difficult Conversations
Conan and Andy Daly reflect on how humor can be a tool for navigating heavy or awkward topics, using their comedic instincts to lower defenses and connect with others.
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