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Magnesium as Prophylaxis for Migraine Headaches
Clinical research · Multiple clinical trials and meta-analyses (0)
Confidence: High
Magnesium supplementation is an effective prophylactic for reducing the frequency and severity of migraines.
Core Concepts
The Problem
Migraines are disabling and often resistant to conventional treatments.
The Claim
Oral magnesium, particularly citrate, can reduce migraine frequency.
Key Evidence
- •Several randomized controlled trials have shown magnesium reduces migraine frequency by about 30-40% compared to placebo.
- •The American Academy of Neurology lists magnesium as a 'probably effective' prophylactic treatment.
- •Mechanisms include vasodilation, NMDA receptor antagonism, and reduction of pro-inflammatory mediators.
Practical Implication
Magnesium is a safe, low-cost supplement that may be used alone or alongside other migraine therapies.
Nuance & Limits
Magnesium is not a cure; response varies, and it may take several weeks to see effects. It is less effective for acute attacks.
Source Material
Videos
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Magnesium and Migraines
Discussion of the evidence
Citation Density
substantial
Gaps
- ⚠ Long-term efficacy data are still needed
- ⚠ Optimal dose and form need further study
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